儿童非侵入性脑刺激：应用与未来方向
NON-INVASIVE BRAIN STIMULATION IN CHILDREN: APPLICATIONS AND FUTURE DIRECTIONS.
作者信息
Rajapakse Thilinie, Kirton Adam
机构信息
Section of Pediatric Neurology, Alberta Children's Hospital Research Institute, Department of Pediatrics and Clinical Neurosciences, University of Calgary, Calgary, AB, Canada.
出版信息
Transl Neurosci. 2013 Jun;4(2). doi: 10.2478/s13380-013-0116-3.
Abstract
Transcranial magnetic stimulation (TMS) is a neurostimulation and neuromodulation technique that has provided over two decades of data in focal, non-invasive brain stimulation based on the principles of electromagnetic induction. Its minimal risk, excellent tolerability and increasingly sophisticated ability to interrogate neurophysiology and plasticity make it an enviable technology for use in pediatric research with future extension into therapeutic trials. While adult trials show promise in using TMS as a novel, non-invasive, non-pharmacologic diagnostic and therapeutic tool in a variety of nervous system disorders, its use in children is only just emerging. TMS represents an exciting advancement to better understand and improve outcomes from disorders of the developing brain.
摘要
经颅磁刺激（TMS）是一种神经刺激和神经调节技术，基于电磁感应原理，它已提供了二十多年有关局灶性、非侵入性脑刺激的数据。其风险极小、耐受性极佳，且在探究神经生理学和可塑性方面的能力日益复杂，这使其成为儿科研究中令人向往的技术，并有望在未来扩展到治疗试验。虽然成人试验显示出将TMS用作多种神经系统疾病的新型、非侵入性、非药物诊断和治疗工具的前景，但它在儿童中的应用才刚刚兴起。TMS是一项令人兴奋的进展，有助于更好地理解发育中脑疾病并改善其治疗结果。
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