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肾下腹主动脉和颈动脉联合重建术:152例患者的早期和晚期结果

Combined infrarenal aorta and carotid artery reconstruction: early and late outcome in 152 patients.

作者信息

Leschi Jean-Pascal, Kieffer Edouard, Chiche Laurent, Koskas Fabien, Bahnini Amine, Benhamou Albert-Claude

机构信息

Department of Vascular Surgery, CHU Pitié Salpêtrière, University Hospital, Paris, France.

出版信息

Ann Vasc Surg. 2002 Mar;16(2):215-24. doi: 10.1007/s10016-001-0162-0. Epub 2002 Mar 20.

Abstract

Between January 1, 1985 and December 31, 1998, we performed combined infrarenal aorta and carotid artery reconstruction in 152 consecutive patients. The mean age of these patients was 65.4 +/- 8.6 years (range, 43-88 years). Infrarenal aortic disease involved abdominal aortic aneurysm in 78 patients (44.7%) and occlusive aortoiliac lesions in 84 (55.3%). Carotid artery disease was detected by performing routine Doppler ultrasonography prior to aortic reconstruction. A total of 121 carotid lesions were asymptomatic (79.6%). A total of 32 patients (21%) had a history of contralateral carotid repair. Eighty-one patients (53.2%) presented with coronary artery disease diagnosed on the basis of clinical and/or laboratory testing. Concurrent lesions were diagnosed in the renal arteries of 43 patients (28.3%) and in the visceral arteries of 16 (10.5%). Based on the results of cardiac evaluation, eight patients underwent coronary revascularization before combined reconstruction. Renal or visceral artery reconstruction was carried out during the same procedure in 30 (19.7%) and 10 (6.6%) patients, respectively. Univariate analysis demonstrated six factors that were significantly associated with perioperative mortality and morbidity: age, coronary artery disease, chronic obstructive pulmonary disease, procedure time, intraoperative blood loss, and creatinemia over 140 micromol/L. Multivariate analysis showed that only the first four of these factors were independent. Actuarial survival in the overall population, including the patients who died during the perioperative period, was 73.9 +/- 7.1% at 5 years and 50.9 +/- 10% at 10 years. From our experience, we conclude that combined infrarenal aorta and carotid artery reconstruction can be performed with no additional operative risks and consequently is the strategy of choice. In our series neither procedure had any effect on the early or late outcome of the other. Our experience suggests that combined surgery is a safe alternative to staged surgery in patients with concurrent lesions involving the infrarenal aorta and carotid artery bifurcation.

摘要

1985年1月1日至1998年12月31日期间,我们对152例连续患者进行了肾下腹主动脉和颈动脉联合重建术。这些患者的平均年龄为65.4±8.6岁(范围43 - 88岁)。肾下腹主动脉疾病包括78例(44.7%)腹主动脉瘤和84例(55.3%)闭塞性主髂动脉病变。在主动脉重建术前通过常规多普勒超声检查发现颈动脉疾病。共有121例颈动脉病变无症状(79.6%)。共有32例患者(21%)有对侧颈动脉修复史。81例患者(53.2%)经临床和/或实验室检查诊断患有冠状动脉疾病。43例患者(28.3%)的肾动脉和16例患者(10.5%)的内脏动脉存在并发病变。根据心脏评估结果,8例患者在联合重建术前接受了冠状动脉血运重建术。分别有30例(19.7%)和10例(6.6%)患者在同一手术过程中进行了肾动脉或内脏动脉重建。单因素分析显示有六个因素与围手术期死亡率和发病率显著相关:年龄、冠状动脉疾病、慢性阻塞性肺疾病、手术时间、术中失血以及肌酐水平超过140微摩尔/升。多因素分析表明其中只有前四个因素是独立的。总体人群的精算生存率,包括围手术期死亡的患者,5年时为73.9±7.1%,10年时为50.9±10%。根据我们的经验,我们得出结论,肾下腹主动脉和颈动脉联合重建术可以在不增加额外手术风险的情况下进行,因此是首选策略。在我们的系列研究中,两种手术对彼此的早期或晚期结果均无影响。我们的经验表明,对于同时累及肾下腹主动脉和颈动脉分叉的并发病变患者,联合手术是分期手术的一种安全替代方案。

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