Short time personalised dialysis: good results in spite of high levels of small and middle molecules.

After almost two years of experience with 43 patients we believe that a short (3 X 4, 3 X 3 hr/week) personalised dialysis is a safe treatment that allows a high survival rate and a good rehabilitation of patients. Pre-dialysis levels of small and middle molecules, the latter only calculated, did not correlate with 5 typical uraemic parameters. Some patients, who formerly experienced standard dialysis, are now equally well or better, without evidence of increasing toxicity, in spite of their higher pre-dialysis levels of small and especially of middle molecules.