Ray-Chaudhuri N, Kiné D Ah, Tijani S O, Parums D V, Cartlidge N, Strong N P, Dayan M R
Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne.
Br J Ophthalmol. 2002 May;86(5):530-2. doi: 10.1136/bjo.86.5.530.
To examine the effect of up to 6 weeks of corticosteroid treatment on the positive temporal artery biopsy rate in giant cell arteritis (GCA).
Prospective comparative clinical study of 11 patients meeting the American College of Rheumatology criteria for diagnosis of GCA. Patients underwent temporal artery biopsy within 1 week, at 2-3 weeks, or after 4 weeks of corticosteroid treatment.
Overall, nine of 11 (82%) patients had positive temporal artery biopsies. Six of seven (86%) biopsies performed after 4 or more weeks of steroid treatment were positive.
Temporal artery biopsy is useful several weeks after institution of steroids.
研究长达6周的皮质类固醇治疗对巨细胞动脉炎(GCA)颞动脉活检阳性率的影响。
对11例符合美国风湿病学会GCA诊断标准的患者进行前瞻性对照临床研究。患者在皮质类固醇治疗1周内、2 - 3周或4周后接受颞动脉活检。
总体而言,11例患者中有9例(82%)颞动脉活检呈阳性。在接受类固醇治疗4周或更长时间后进行的7次活检中有6次(86%)呈阳性。
在使用类固醇治疗数周后进行颞动脉活检是有用的。