[华盛顿大学生活质量问卷用于中国喉癌随访的可行性]

[Feasibility of University of Washington-Quality of Life questionnaire for follow up of laryngeal cancer in China].

作者信息

Wang Guojian, Ji Wenyue, Pan Zimin, Guo Xing

机构信息

Department of Otorhinolaryngology, First Hospital, China Medical University, Shenyang 110001, China.

出版信息

Zhonghua Zhong Liu Za Zhi. 2002 Jan;24(1):53-6.

PMID:11977640

Abstract

OBJECTIVE

To assess the feasibility of University of Washington Quality of Life (UW-QOL) questionnaire in laryngeal cancer patients treated by total or partial laryngectomy and their prognostic factors in China.

METHODS

With UW-QOL questionnaire, a survey was conducted in patients treated by partial (81, Group A) or total (37, Group B) laryngectomy for laryngeal cancer.

RESULTS

The composite QOL scores of group A (692.34 +/- 127.94) were higher than those of group B (636.35 +/- 139.97), with a difference statistically significant (P < 0.05). Group A (74.32 +/- 23.82; 80.86 +/- 20.26) was better than group B (40.27 +/- 25.76; 69.59 +/- 27.09) in speech and appearance (P < 0.001; P < 0.05); but group B (92.57 +/- 13.00) was superior to group A (83.02 +/- 20.47) in pain (P < 0.01). Six factors including stage, operative, modality, complication, postoperative radiotherapy or chemotherapy, with whom to live, chronic disease before or after operation were related to postlaryngectomy QOL.

CONCLUSION

Partial laryngectomy is superior to total laryngectomy in speech, appearance and overall QOL. UW-QOL questionnaire is suitable for QOL research in laryngeal cancer in China.

摘要

目的

评估华盛顿大学生活质量（UW-QOL）问卷在中国喉癌全喉或部分喉切除患者中的可行性及其预后因素。

方法

采用UW-QOL问卷对81例接受部分喉切除（A组）和37例接受全喉切除（B组）的喉癌患者进行调查。

结果

A组的综合生活质量得分（692.34±127.94）高于B组（636.35±139.97），差异有统计学意义（P<0.05）。A组在言语和外观方面（74.32±23.82；80.86±20.26）优于B组（40.27±25.76；69.59±27.09）（P<0.001；P<0.05）；但B组在疼痛方面（92.57±13.00）优于A组（83.02±20.47）（P<0.01）。包括分期、手术方式、并发症、术后放疗或化疗、与谁同住、术前或术后慢性病在内的六个因素与喉切除术后生活质量相关。