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儿童哮喘的气雾剂给药系统

Aerosol delivery systems in childhood asthma.

作者信息

Chauhan S, Gogtay J A

机构信息

Medical and Research Department, Cipla Ltd, Mumbai.

出版信息

Indian J Pediatr. 2001 Sep;68 Suppl 4:S17-22.

PMID:11980464
Abstract

Asthma in younger children appears to be increasing in prevalence, whilst at the same time it is recognized that inhaled corticosteroids and bronchodilators are the mainstay of treatment for this condition. Presently the devices available for aerosol treatment of young children are mostly developed for use in older children and adults. However, an awareness of the need for delivery systems dedicated to use by young children is increasing. The devices available at present for aerosol treatment of young children comprises the nebulizer, metered-dose inhaler with spacer, and dry powder inhaler. The inhaler strategy found most useful at present can be summarized as follows: children younger than 2 years can use MDI+spacer+mask or nebulization, while children above 2 years can use MDI+spacer (without mask). Older children (3-4 years) can be easily taught the use of a Rotahaler.

摘要

年幼儿童哮喘的患病率似乎在上升,与此同时,人们认识到吸入性糖皮质激素和支气管扩张剂是这种疾病治疗的主要手段。目前,用于幼儿雾化治疗的装置大多是为大龄儿童和成人设计的。然而,对专门供幼儿使用的给药系统的需求意识正在增强。目前可用于幼儿雾化治疗的装置包括雾化器、带储雾罐的定量吸入器和干粉吸入器。目前发现最有用的吸入器使用策略可总结如下:2岁以下儿童可使用定量吸入器+储雾罐+面罩或雾化治疗,而2岁以上儿童可使用定量吸入器+储雾罐(不使用面罩)。年龄稍大的儿童(3 - 4岁)可以很容易学会使用旋转式吸入器。

相似文献

1
Aerosol delivery systems in childhood asthma.儿童哮喘的气雾剂给药系统
Indian J Pediatr. 2001 Sep;68 Suppl 4:S17-22.
2
[Treatment of asthma using aerosols].[使用气雾剂治疗哮喘]
Allergol Immunopathol (Madr). 1996 Jul-Aug;24(4):139-45.
3
Delivery systems: the science.递送系统:科学
Pediatr Pulmonol Suppl. 1997 Sep;15:51-4.
4
Randomized comparison of a dry powder inhaler and metered dose inhaler with spacer in management of children with asthma.干粉吸入器与定量气雾剂加储雾罐治疗儿童哮喘的随机对照研究
Indian Pediatr. 2001 Jan;38(1):24-8.
5
Key issues in inhalation therapy in children.儿童吸入疗法中的关键问题。
Curr Med Res Opin. 2005;21 Suppl 4:S27-32. doi: 10.1185/030079905X61767.
6
Randomized controlled trial of salbutamol aerosol therapy via metered dose inhaler-spacer vs. jet nebulizer in young children with wheezing.沙丁胺醇气雾剂通过定量吸入器-储雾罐与喷射雾化器治疗幼儿喘息的随机对照试验
Pediatr Pulmonol. 2005 May;39(5):466-72. doi: 10.1002/ppul.20204.
7
Measurement of peak inspiratory flow with in-check dial device to simulate low-resistance (Diskus) and high-resistance (Turbohaler) dry powder inhalers in children with asthma.使用内置刻度盘装置测量哮喘儿童吸入峰值流速,以模拟低阻力(都保)和高阻力(准纳器)干粉吸入器。
Pediatr Pulmonol. 2005 May;39(5):447-51. doi: 10.1002/ppul.20180.
8
Comparing clinical features of the nebulizer, metered-dose inhaler, and dry powder inhaler.比较雾化器、定量吸入器和干粉吸入器的临床特征。
Respir Care. 2005 Oct;50(10):1313-21; discussion 1321-2.
9
Aerosol therapy.雾化疗法。
Respir Care Clin N Am. 1995 Dec;1(2):235-63.
10
[Update on inhalation therapy in asthma and obstructive bronchopulmonary diseases].[哮喘和阻塞性支气管肺疾病吸入疗法的最新进展]
Union Med Can. 1994 Jan;123(1):23-31.

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