人肺孢子菌对严重联合免疫缺陷小鼠无传染性。
Pneumocystis carinii f. sp. hominis is not infectious for SCID mice.
作者信息
Durand-Joly Isabelle, Aliouat El Moukhtar, Recourt Céline, Guyot Karine, François Nadine, Wauquier Michèle, Camus Daniel, Dei-Cas Eduardo
机构信息
Ecologie du Parasitisme, Institut Pasteur de Lille, 1 rue du Prof-Calmette-BP 245, 59019 Lille, France.
出版信息
J Clin Microbiol. 2002 May;40(5):1862-5. doi: 10.1128/JCM.40.5.1862-1865.2002.
Abstract
The infectious power of Pneumocystis carinii f. sp. hominis was explored by inoculating SCID mice intranasally with either P. carinii f. sp. hominis or P. carinii f. sp. muris isolates. Only mice inoculated with mouse parasites developed Pneumocystis pneumonia, as assessed by microscopy and PCR. These results suggest that humans do not contract pneumocystosis from animals.
摘要
通过给SCID小鼠经鼻接种人型卡氏肺孢子虫或鼠型卡氏肺孢子虫分离株来探究人型卡氏肺孢子虫的感染能力。通过显微镜检查和聚合酶链反应评估，只有接种了鼠类寄生虫的小鼠患上了卡氏肺孢子虫肺炎。这些结果表明人类不会从动物身上感染肺孢子虫病。
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