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人肺孢子菌对严重联合免疫缺陷小鼠无传染性。

Pneumocystis carinii f. sp. hominis is not infectious for SCID mice.

作者信息

Durand-Joly Isabelle, Aliouat El Moukhtar, Recourt Céline, Guyot Karine, François Nadine, Wauquier Michèle, Camus Daniel, Dei-Cas Eduardo

机构信息

Ecologie du Parasitisme, Institut Pasteur de Lille, 1 rue du Prof-Calmette-BP 245, 59019 Lille, France.

出版信息

J Clin Microbiol. 2002 May;40(5):1862-5. doi: 10.1128/JCM.40.5.1862-1865.2002.

DOI:10.1128/JCM.40.5.1862-1865.2002
PMID:11980979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC130940/
Abstract

The infectious power of Pneumocystis carinii f. sp. hominis was explored by inoculating SCID mice intranasally with either P. carinii f. sp. hominis or P. carinii f. sp. muris isolates. Only mice inoculated with mouse parasites developed Pneumocystis pneumonia, as assessed by microscopy and PCR. These results suggest that humans do not contract pneumocystosis from animals.

摘要

通过给SCID小鼠经鼻接种人型卡氏肺孢子虫或鼠型卡氏肺孢子虫分离株来探究人型卡氏肺孢子虫的感染能力。通过显微镜检查和聚合酶链反应评估，只有接种了鼠类寄生虫的小鼠患上了卡氏肺孢子虫肺炎。这些结果表明人类不会从动物身上感染肺孢子虫病。

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Pneumocystis carinii f. sp. hominis is not infectious for SCID mice.人肺孢子菌对严重联合免疫缺陷小鼠无传染性。
J Clin Microbiol. 2002 May;40(5):1862-5. doi: 10.1128/JCM.40.5.1862-1865.2002.
2
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本文引用的文献

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In vitro systems in pneumocystis research.肺孢子菌研究中的体外系统。
Parasitol Today. 1996 Jun;12(6):245-9. doi: 10.1016/0169-4758(96)80812-x.
2
Phylogeny of Pneumocystis carinii from 18 primate species confirms host specificity and suggests coevolution.来自18种灵长类动物的卡氏肺孢子虫的系统发育证实了宿主特异性并表明了共同进化。
J Clin Microbiol. 2001 Jun;39(6):2126-33. doi: 10.1128/JCM.39.6.2126-2133.2001.
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Search for primary infection by Pneumocystis carinii in a cohort of normal, healthy infants.在一组正常、健康的婴儿中寻找卡氏肺囊虫的原发性感染情况。
Clin Infect Dis. 2001 Mar 15;32(6):855-61. doi: 10.1086/319340. Epub 2001 Mar 9.
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Pneumocystis infections: the iceberg?肺孢子菌感染：冰山一角？
Med Mycol. 2000;38 Suppl 1:23-32.
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Transmission of Pneumocystis carinii disease from immunocompetent contacts of infected hosts to susceptible hosts.卡氏肺孢子虫病从受感染宿主的免疫功能正常接触者传播至易感宿主。
Eur J Clin Microbiol Infect Dis. 2000 Sep;19(9):671-8. doi: 10.1007/s100960000354.
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Ultrastructural and molecular characterization of Pneumocystis carinii isolated from a rhesus monkey (Macaca mulatta).从恒河猴（猕猴属）分离出的卡氏肺孢子虫的超微结构和分子特征
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Pneumocystis carinii growth kinetics in culture systems and in hosts: involvement of each life cycle parasite stage.卡氏肺孢子虫在培养系统和宿主体内的生长动力学：各生命周期寄生虫阶段的参与情况
J Eukaryot Microbiol. 1999 Sep-Oct;46(5):116S-117S.
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Experimental inoculation of immunosuppressed owl monkeys with Pneumocystis carinii f. sp. hominis.用卡氏肺孢子虫人型变种对免疫抑制的夜猴进行实验性接种。
J Eukaryot Microbiol. 1999 Sep-Oct;46(5):113S-115S.
9
P.carinii host specificity: attempt of cross infections with human derived strains in rats.卡氏肺孢子虫的宿主特异性：用人源菌株在大鼠中进行交叉感染的尝试。
J Eukaryot Microbiol. 1999 Sep-Oct;46(5):112S.
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Genetics, metabolism and host specificity of Pneumocystis carinii.卡氏肺孢子虫的遗传学、代谢及宿主特异性
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