在酵母基因组中筛选新的DNA修复基因。
Screening the yeast genome for new DNA-repair genes.
作者信息
Jazayeri Ali, Jackson Stephen P
机构信息
Wellcome/Cancer Research UK Institute of Cancer and Developmental Biology and Department of Zoology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.
出版信息
Genome Biol. 2002;3(4):REVIEWS1009. doi: 10.1186/gb-2002-3-4-reviews1009. Epub 2002 Mar 13.
Abstract
Studies of DNA repair and the maintenance of genomic integrity are essential to understanding the etiology and pathology of cancer. The availability of the complete genome sequence of Saccharomyces cerevissiae has greatly facilitated the discovery of new genes important for DNA repair.
摘要
对DNA修复和基因组完整性维持的研究对于理解癌症的病因和病理至关重要。酿酒酵母完整基因组序列的可得性极大地促进了对DNA修复重要新基因的发现。
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