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1966 - 1987年英格兰和威尔士人口普查区的人口混合情况与儿童白血病和非霍奇金淋巴瘤

Population mixing and childhood leukaemia and non-Hodgkin's lymphoma in census wards in England and Wales, 1966-87.

作者信息

Dickinson Heather O, Hammal D M, Bithell J F, Parker L

机构信息

North of England Children's Cancer Research Unit, Department of Child Health, University of Newcastle, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK.

出版信息

Br J Cancer. 2002 May 6;86(9):1411-3. doi: 10.1038/sj.bjc.6600275.

DOI:10.1038/sj.bjc.6600275
PMID:11986772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2375373/
Abstract

We found an increased risk of childhood leukaemia with higher levels of inward migration, particularly from outside the region (rate ratio=1.9, 95%CI: 1.2-2.9, P<0.01). This significant effect was observed only in urban areas, although a marked but non-significant effect was seen in affluent, rural areas.

摘要

我们发现,随着向内迁移水平的提高,儿童白血病风险增加,尤其是来自该地区以外的迁移(率比=1.9,95%置信区间:1.2-2.9,P<0.01)。仅在城市地区观察到这种显著影响,尽管在富裕的农村地区也观察到了明显但不显著的影响。

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本文引用的文献

1
Quantifying the effect of population mixing on childhood leukaemia risk: the Seascale cluster.量化人群混合对儿童白血病风险的影响:西斯科尔集群研究
Br J Cancer. 1999 Sep;81(1):144-51. doi: 10.1038/sj.bjc.6690664.
2
Effect of population mixing and socioeconomic status in England and Wales, 1979-85, on lymphoblastic leukaemia in children.1979 - 1985年英格兰和威尔士人口混合及社会经济地位对儿童淋巴细胞白血病的影响。
BMJ. 1996 Nov 23;313(7068):1297-300. doi: 10.1136/bmj.313.7068.1297.
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Controlling for socioeconomic confounding using regression methods.使用回归方法控制社会经济混杂因素。
J Epidemiol Community Health. 1995 Dec;49 Suppl 2(Suppl 2):S15-9. doi: 10.1136/jech.49.suppl_2.s15.
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Maximum likelihood estimation of the attributable fraction from logistic models.逻辑模型中归因分数的最大似然估计。
Biometrics. 1993 Sep;49(3):865-72.
5
Distribution of childhood leukaemias and non-Hodgkin's lymphomas near nuclear installations in England and Wales.英格兰和威尔士核设施附近儿童白血病和非霍奇金淋巴瘤的分布情况。
BMJ. 1994;309(6953):501-5. doi: 10.1136/bmj.309.6953.501.