Neuhaus James D, Oost Rik, Merad Jérémy, Maulide Nuno
Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria.
Top Curr Chem (Cham). 2018 Apr 13;376(3):15. doi: 10.1007/s41061-018-0193-4.
Traditionally employed in the synthesis of small ring systems and rearrangement chemistry, sulfur-based ylides occupy a unique position in the toolbox of the synthetic organic chemist. In recent years a number of pioneering researchers have looked to expand the application of these unorthodox reagents through the use of transition metal catalysis. The strength and flexibility of such a combination have been shown to be of key importance in developing powerful novel methodologies. This chapter summarises recent developments in transition metal-catalysed sulfonium/sulfoxonium ylide reactions, as well as providing a historical perspective. In overviewing the successes in this area, the authors hope to encourage others into this growing field.
硫叶立德传统上用于小环体系的合成和重排化学，在有机合成化学家的工具库中占据独特地位。近年来，一些开创性的研究人员试图通过过渡金属催化来扩大这些非传统试剂的应用。事实证明，这种组合的强度和灵活性对于开发强大的新方法至关重要。本章总结了过渡金属催化的锍/氧化锍叶立德反应的最新进展，并提供了历史视角。在概述该领域的成功时，作者希望鼓励其他人进入这个不断发展的领域。
