Herbener Ellen S, Harrow Martin
Department of Psychiatry, University of Illinois at Chicago, 60612, USA.
J Abnorm Psychol. 2002 May;111(2):237-48.
Although anhedonia has been proposed to be a trait-like characteristic in schizophrenia patients, its persistence and stability have not been tested using multiple assessments over a multiyear period. Specific definitions of anhedonia vary across studies, and relationships between different types of anhedonia as well as their relationship to schizophrenic symptoms over the course of illness have not been addressed. The current research, using prospectively collected longitudinal data covering a 10-year span for 127 individuals with schizophrenic illness, found that (a) physical, but not depressive, anhedonia is a stable characteristic over a 10-year period; (b) physical anhedonia does not show strong and consistent relationships with psychotic, negative, or depressive symptoms; and (c) the relationship between some premorbid characteristics and physical anhedonia are significant even 10 years into the course of illness.
尽管快感缺失被认为是精神分裂症患者的一种特质样特征，但尚未通过多年的多次评估来测试其持续性和稳定性。快感缺失的具体定义在不同研究中有所不同，不同类型的快感缺失之间的关系以及它们在疾病过程中与精神分裂症症状的关系尚未得到探讨。当前的研究使用前瞻性收集的涵盖127名精神分裂症患者10年跨度的纵向数据，发现：（a）身体性快感缺失而非抑郁性快感缺失在10年期间是一个稳定的特征；（b）身体性快感缺失与精神病性、阴性或抑郁性症状没有强烈且一致的关系；（c）即使在患病10年后，一些病前特征与身体性快感缺失之间的关系仍然显著。
