Eddy Sean R
Howard Hughes Medical Institute, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Cell. 2002 Apr 19;109(2):137-40. doi: 10.1016/s0092-8674(02)00727-4.
The number of known noncoding RNA genes is expanding rapidly. Computational analysis of genome sequences, which has been revolutionary for protein gene analysis, should also be able to address questions of the number and diversity of noncoding RNA genes. However, noncoding RNAs present computational genomics with a new set of challenges.
已知的非编码RNA基因数量正在迅速增加。基因组序列的计算分析在蛋白质基因分析方面具有革命性意义,对于解决非编码RNA基因的数量和多样性问题也应具有同样的作用。然而,非编码RNA给计算基因组学带来了一系列新的挑战。