铜（I）-吡唑啉酮配合物催化的末端炔烃对亚胺的对映选择性直接加成反应在水和甲苯中的研究
Enantioselective direct-addition of terminal alkynes to imines catalyzed by copper(I)pybox complex in water and in toluene.
作者信息
Wei Chunmei, Li Chao-Jun
机构信息
Department of Chemistry, Tulane University, New Orleans, Louisiana 70118, USA.
出版信息
J Am Chem Soc. 2002 May 22;124(20):5638-9. doi: 10.1021/ja026007t.
PMID:12010027
Abstract
Highly enantioselective direct alkyne-imine additions catalyzed by Cu(I)OTf and Evan's pybox ligands were developed in water and in toluene. The process is simple and provides a diverse range of propargylic amine in high ee and good yield.
摘要
由三氟甲磺酸铜（I）和埃文斯吡唑啉酮配体催化的高度对映选择性直接炔烃-亚胺加成反应在水和甲苯中得以实现。该过程简单，能以高对映体过量（ee）和良好产率提供多种炔丙基胺。
Zotero 插件