Berg M H, Manninen H I, Räsänen H T, Vanninen R L, Jaakkola P A
Department of Clinical Radiology, University Hospital, Kuopio, Finland.
Acta Radiol. 2002 Mar;43(2):116-24. doi: 10.1080/028418502127347763.
The aim of the study was to evaluate the ability of CT angiography (CTA) to detect atherosclerosis of the carotid arteries in comparison with 3D time-of-flight MR angiography (3D TOF MRA), using contrast angiography and intravascular ultrasound (IVUS) as a reference.
Contrast angiography and CTA were performed in 31 patients (mean age 65 years, range 45-79). The image quality was evaluated, atherosclerotic lesions were registered, and diameter stenosis degree was visually estimated from axial source images of CTA and 3D TOF MRA (21 patients), and results of interpretations were compared. The comparison of quantitative measurements was performed using IVUS as a reference.
Contrast angiography detected 51 lesions (mean diameter stenosis 50%, range 10-100%), and CTA detected all same lesions. CTA provided better image quality and consistency of image interpretation than 3D TOF MRA. IVUS verified 29 atherosclerotic lesions with a mean diameter stenosis of 35%, (range 4-40%). CTA yielded a sensitivity of 96% to 100% (< or =10% or < or =20% diameter stenosis regarded as normal) for the detection of lesions with reference to IVUS.
CTA seems feasible and accurate for the detection of atherosclerosis in carotid arteries.
本研究旨在对比CT血管造影（CTA）与三维时间飞跃磁共振血管造影（3D TOF MRA）检测颈动脉粥样硬化的能力，以对比血管造影和血管内超声（IVUS）作为参照标准。
对31例患者（平均年龄65岁，范围45 - 79岁）进行了对比血管造影和CTA检查。评估图像质量，记录动脉粥样硬化病变，并从CTA和3D TOF MRA的轴位源图像上目测估计直径狭窄程度（21例患者），并对解读结果进行比较。以IVUS作为参照标准进行定量测量比较。
对比血管造影检测到51处病变（平均直径狭窄50%，范围10 - 100%），CTA检测到了所有相同病变。与3D TOF MRA相比，CTA提供了更好的图像质量和图像解读一致性。IVUS证实了29处动脉粥样硬化病变，平均直径狭窄35%（范围4 - 40%）。以IVUS为参照，CTA对病变检测的敏感度为96%至100%（直径狭窄≤10%或≤20%视为正常）。
CTA在检测颈动脉粥样硬化方面似乎可行且准确。
