Rakow A L, Hochmuth R M
Biophys J. 1975 Nov;15(11):1095-100. doi: 10.1016/S0006-3495(75)85885-1.
A parallel plate flow channel is employed to study the effect of heat treatment on the elasticity of human red cell membrane. An irreversible transition between 46 degrees C and 50 degrees C results in an approximately 200% increase in an elastic constant measured at 25 degrees C. This transition is attributable to irreversible protein denaturation which has been shown by other to occur at similar temperatures in calorimetric studies of red cell ghosts.
采用平行板流动通道来研究热处理对人红细胞膜弹性的影响。在46摄氏度至50摄氏度之间的不可逆转变导致在25摄氏度下测得的弹性常数增加约200%。这种转变归因于不可逆的蛋白质变性,在其他关于红细胞血影的量热研究中已表明在类似温度下会发生这种变性。