应用于流体剪切和微量移液器变形红细胞分析的新膜概念。
New membrane concept applied to the analysis of fluid shear- and micropipette-deformed red blood cells.
作者信息
Evans E A
出版信息
Biophys J. 1973 Sep;13(9):941-54. doi: 10.1016/S0006-3495(73)86036-9.
Abstract
A two-dimensional elastomer material concept of the red cell membrane is applied to the analysis of fluid shear-deformed, point-attached red cells and micropipette aspiration of red cell disks. The elastic constant (corresponding to the "shear" modulus multiplied by the membrane thickness) is of the order 10(-2) dyn/cm for both cases. Additional experimental observations are in agreement with the membrane model, e.g. teardrop and "tether" formation of the sheared disks, pressure difference vs. aspirated length of the cell for micropipette experiments, etc
摘要
红细胞膜的二维弹性体材料概念被应用于对流体剪切变形、点附着红细胞以及红细胞圆盘的微量吸管抽吸的分析。在这两种情况下，弹性常数（对应于“剪切”模量乘以膜厚度）约为10^(-2) 达因/厘米。其他实验观察结果与该膜模型相符，例如剪切圆盘的泪滴状和“系链”形成、微量吸管实验中细胞的压力差与抽吸长度的关系等。
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本文引用的文献
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MECHANICAL PROPERTIES OF THE RED CELL MEMBRANE. II. VISCOELASTIC BREAKDOWN OF THE MEMBRANE.红细胞膜的力学性质。II. 膜的粘弹性破坏
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Strain energy function of red blood cell membranes.红细胞膜的应变能函数。
Biophys J. 1973 Mar;13(3):245-64. doi: 10.1016/S0006-3495(73)85983-1.
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