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用于评估葡萄膜黑色素瘤巩膜侵犯及巩膜外扩展的磁共振成像

MRI for the evaluation of scleral invasion and extrascleral extension of uveal melanomas.

作者信息

Récsán Zsuzsa, Karlinger Kinga, Fodor Magdolna, Zalatnai Attila, Papp Melitta, Salacz György

机构信息

Second Department of Ophthalmology, Faculty Medicine, Semmelweis University, Budapest, Hungary.

出版信息

Clin Radiol. 2002 May;57(5):371-6. doi: 10.1053/crad.2001.0859.

Abstract

AIM

To study the diagnostic value of MRI for the detection of scleral infiltration and extrascleral extension of uveal melanoma.

MATERIALS AND METHODS

Twelve consecutive patients with clinically suspected large uveal melanoma were examined by MRI. All of the patients underwent enucleation or exenteration. The clinical and histopathological findings were compared.

RESULTS

The clinical diagnosis of uveal malignant melanoma was confirmed by histology in each case. MRI allowed detection of scleral infiltration with a sensitivity of 100% and a specificity of 50%. For extrascleral extension, MRI had a sensitivity of 100% and specificity of 89%.

CONCLUSIONS

Using fat suppression technique and enhancement with contrast medium, MRI proved to be a valuable ancillary method for the assessment of scleral infiltration and extrascleral extension.

摘要

目的

研究磁共振成像(MRI)对检测葡萄膜黑色素瘤巩膜浸润和巩膜外扩展的诊断价值。

材料与方法

对12例临床怀疑为大的葡萄膜黑色素瘤的连续患者进行了MRI检查。所有患者均接受了眼球摘除术或眶内容剜除术。比较临床和组织病理学检查结果。

结果

每例患者经组织学证实为葡萄膜恶性黑色素瘤。MRI检测巩膜浸润的灵敏度为100%,特异度为50%。对于巩膜外扩展,MRI的灵敏度为100%,特异度为89%。

结论

通过使用脂肪抑制技术和造影剂增强,MRI被证明是评估巩膜浸润和巩膜外扩展的一种有价值的辅助方法。

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