Nusbaum Michael P, Beenhakker Mark P
Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia 19104-6074, USA.
Nature. 2002 May 16;417(6886):343-50. doi: 10.1038/417343a.
How neuronal networks enable animals, humans included, to make coordinated movements is a continuing goal of neuroscience research. The stomatogastric nervous system of decapod crustaceans, which contains a set of distinct but interacting motor circuits, has contributed significantly to the general principles guiding our present understanding of how rhythmic motor circuits operate at the cellular level. This results from a detailed documentation of the circuit dynamics underlying motor pattern generation in this system as well as its modulation by individual transmitters and neurons.
神经网络如何使包括人类在内的动物能够进行协调运动,是神经科学研究的一个持续目标。十足目甲壳动物的口胃神经系统包含一组独特但相互作用的运动回路,这对指导我们目前理解节律性运动回路在细胞水平上如何运作的一般原则做出了重大贡献。这得益于对该系统中运动模式产生背后的回路动力学及其由单个递质和神经元进行的调节的详细记录。