[百合化学成分的研究]

[Studies on chemical constituents of Lilium brownii].

作者信息

Hou X, Chen F

机构信息

Shenyang Pharmaceutical University, Shenyang 110015.

出版信息

Yao Xue Xue Bao. 1998 Dec;33(12):923-6.

PMID:12016858

Abstract

Lilium brownii F. E. Brown var. viridulum Baker is a well-known and very important traditional Chinese medicine. It has been used as sedative, antitussive, anti-inflammatory or as a nutrient. Five compounds were isolated from the bulbs of Lilium brownii. On the basis of spectroscopic analysis (IR, FAB-MS, 1HNMR, 13CNMR, DEPT, HMQC, HMBC) and their physicochemical properties, they were identified as beta-sitosterol (I), daucosterol (II), n-butyl-beta-D-fructopyranoside (III), 26-O-beta-D-glucopyranosyl-3 beta, 26-dihydroxy-5-cholesten-16, 22-dioxo-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside (IV), 26-O-beta-D-glucopyranosyl-3beta, 26-dihydroxy cholestan-16, 22-dioxo-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside(V). Among them, I, II and III were isolated from this plant for the first time, IV and V are new compounds.

摘要

百合（Lilium brownii F. E. Brown var. viridulum Baker）是一种著名且非常重要的传统中药。它被用作镇静剂、止咳剂、抗炎药或营养剂。从百合鳞茎中分离出了五种化合物。根据光谱分析（红外光谱、快原子轰击质谱、核磁共振氢谱、核磁共振碳谱、无畸变极化转移增强谱、异核多量子相干谱、异核多键相关谱）及其理化性质，它们被鉴定为β-谷甾醇（I）、胡萝卜苷（II）、正丁基-β-D-吡喃果糖苷（III）、26-O-β-D-吡喃葡萄糖基-3β,26-二羟基-5-胆甾烯-16,22-二酮-3-O-α-L-鼠李糖基-(1→2)-β-D-吡喃葡萄糖苷（IV）、26-O-β-D-吡喃葡萄糖基-3β,26-二羟基胆甾烷-16,22-二酮-3-O-α-L-鼠李糖基-(1→2)-β-D-吡喃葡萄糖苷（V）。其中，I、II和III是首次从该植物中分离得到，IV和V是新化合物。