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[核黄素对大鼠脂质过氧化的影响]

[The effect of riboflavin on lipid peroxidation in rats].

作者信息

Liang H, Liu Q, Xu J

机构信息

Department of Nutrition and Food Hygiene, School of Public Health, Shanghai Medical University, Shanghai 200032, China.

出版信息

Wei Sheng Yan Jiu. 1999 Nov;28(6):370-1.

PMID:12016993
Abstract

In order to study the effect of riboflavin on lipid peroxidation in rats, randomized block design was used to study the effect of different riboflavin levels on the riboflavin status and lipid peroxidation of S.D. rats. The rats fed with riboflavin deficient diets for 6 weeks had higher levels of BGRAC, blood malondialdehyde and lower levels of GSH than those with riboflavin sufficient diets. The RBC SOD activity is also reduced in riboflavin deficiency rats. It is concluded that riboflavin deficiency increases the extent of lipid peroxidation.

摘要

为研究核黄素对大鼠脂质过氧化的影响,采用随机区组设计研究不同核黄素水平对SD大鼠核黄素状态及脂质过氧化的影响。与喂食核黄素充足日粮的大鼠相比,喂食核黄素缺乏日粮6周的大鼠具有更高水平的BGRAC、血液丙二醛以及更低水平的谷胱甘肽。核黄素缺乏的大鼠红细胞超氧化物歧化酶活性也降低。结论是核黄素缺乏会增加脂质过氧化程度。

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