Ishii Junnosuke, Fujita Kunio, Komori Takahide
Department of Oral and Maxillofacial Surgery, Kobe University School of Medicine, Japan.
J Clin Laser Med Surg. 2002 Apr;20(2):57-61. doi: 10.1089/104454702753768025.
Laser monotherapy for squamous cell carcinoma of the mobile tongue treated with CO2 laser was carried out on 18 cases between 1979 and 1997.
Three cases recurred after laser surgery. As a subsequent therapy, radiotherapy was performed on two of them and laser surgery was repeated on the remaining one. No recurrences were found in the two patients who died from other diseases after laser surgery.
The cure rate of primary tumors was 83.3%. One patient had subsequent metastasis after laser surgery. The rate of recurrence and subsequent metastasis was compared between a group of patients treated with laser surgery and a group treated with radiotherapy (interstitial implant). No differences were found in the rate of recurrence between the two groups. While 22 of 52 patients had a subsequent metastasis in the group treated with interstitial implant, only one patient had it in the group treated with laser surgery. There was a statistical difference between these two groups (p < 0.01).
1979年至1997年间，对18例舌活动部鳞状细胞癌患者采用二氧化碳激光进行激光单一疗法治疗。
3例患者激光手术后复发。作为后续治疗，其中2例接受了放射治疗，另1例再次接受了激光手术。2例激光手术后因其他疾病死亡的患者未出现复发。
原发肿瘤的治愈率为83.3%。1例患者激光手术后出现转移。比较了激光手术治疗组和放射治疗（间质植入）组的复发率和后续转移率。两组的复发率无差异。间质植入治疗组的52例患者中有22例出现后续转移，而激光手术治疗组仅有1例出现后续转移。两组之间存在统计学差异（p < 0.01）。
