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KTP 532激光辅助手术治疗口腔恶性肿瘤——一项回顾性研究

KTP 532 Laser Assisted Surgery for Oral Cavity Malignancy-A Retrospective Study.

作者信息

Nayak Dipak Ranjan, Balakrishnan R, Dalakoti Pooja, Bhanu Uday, Nair Suraj, Poojary Kailesh

机构信息

Former Professor and Head of Department, Dept of Otorhinolaryngology- Head and Neck Surgery, Kasturba Medical College, Manipal, India.

Professor , Dept of Otorhinolaryngology- Head and Neck Surgery, Kasturba Medical College, Manipal, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Jun;75(2):416-419. doi: 10.1007/s12070-022-03214-x. Epub 2022 Nov 17.

Abstract

AIMS AND OBJECTIVE

To determine the effectiveness of KTP 532 in surgically treating early and early advanced oral malignancy with no surgical reconstruction of primary site.

MATERIALS AND METHODS

It is a retrospective study of 67 cases operated between 2000 to 2013 including T1, T2 and Early T3 cases, approved by ethical committee. All the cases underwent Laser assisted excision of tumour with or without Neck Dissection or Adjuvant Radiotherapy. Age of the cases varied from 20 to 80 years with mean age of 49 years. 47 cases were males and 20 were females. 26 cases in the study had neck nodes clinically whereas 41 cases had N0 status. Neck dissection was done (SOND or MRND) in 61 cases. In 6 cases (N0) no neck dissection was done.

RESULTS

61 cases had no loco-regional residual disease on their last follow up. Six cases had loco-regional recurrence within 6 months and salvage surgery was done. The overall mean survival was 81 months (92, 82 and 71 months in Stage I, II,III respectively). 3 year disease free survival rate was 91% as calculated using Kaplan- Meier Scale. In all these cases tumour was excised with KTP 532 laser and no reconstruction was done. Wound was allowed to heal with secondary intention.

CONCLUSION

Laser assisted excision of oral malignancy is an alternative to conventional treatment with more precision, less morbidity, shorter hospital stay and better functional outcomes.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s12070-022-03214-x.

摘要

目的

确定KTP 532激光在不进行原发部位手术重建的情况下,对外科治疗早期及早期进展期口腔恶性肿瘤的有效性。

材料与方法

这是一项回顾性研究,研究对象为2000年至2013年间接受手术的67例患者,包括T1、T2和早期T3病例,经伦理委员会批准。所有病例均接受了激光辅助肿瘤切除术,可选择进行或不进行颈部清扫或辅助放疗。病例年龄在20至80岁之间,平均年龄为49岁。男性47例,女性20例。研究中有26例临床检查发现颈部有淋巴结,41例为N0状态。61例行颈部清扫术(选择性颈清扫术或改良根治性颈清扫术)。6例(N0)未行颈部清扫术。

结果

61例患者在最后一次随访时无局部区域残留疾病。6例在6个月内出现局部区域复发并接受了挽救性手术。总体平均生存期为81个月(I期、II期、III期分别为92个月、82个月和71个月)。使用Kaplan-Meier量表计算的3年无病生存率为91%。在所有这些病例中,均使用KTP 532激光切除肿瘤,未进行重建。伤口通过二期愈合。

结论

激光辅助切除口腔恶性肿瘤是一种替代传统治疗的方法,具有更高的精确性、更低的发病率、更短的住院时间和更好的功能预后。

补充信息

在线版本包含可在10.1007/s12070-022-03214-x获取的补充材料。

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