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日本结核病的当前流行病学趋势。

Current epidemiological trend of tuberculosis in Japan.

作者信息

Ohmori M, Ishikawa N, Yoshiyama T, Uchimura K, Aoki M, Mori T

机构信息

The Research Institute of Tuberculosis, Tokyo, Japan.

出版信息

Int J Tuberc Lung Dis. 2002 May;6(5):415-23.

Abstract

OBJECTIVE

To observe the recent epidemiological trend of tuberculosis and to determine the factors related to the deteriorating trend in incidence and mortality rates in Japan.

DESIGN

Descriptive analyses of tuberculosis notification rates and mortality rates by age, sex, year and birth-cohort.

RESULTS

The decline in the tuberculosis notification rate has started slowing down since around 1980. Among the cohorts born before 1950, the trend of notification rate by age has levelled off since around 1980. The reduction in the tuberculosis mortality rate has also recently begun to slow down, but later and to a lesser extent than that of the notification rate. Although deaths due to tuberculosis occur mostly among the elderly, the rate of decline in mortality among middle-aged males has slowed down recently. The trend in the mortality rate of birth-cohorts has recently shown an upward trend with age.

CONCLUSION

A major cause of the current stagnation of the decline in notification rates is the increase in the elderly population with a high prevalence of tuberculosis infection in the past, who are more likely to develop the disease as they approach biological senescence. Other possible causes are a gradual shift of the tuberculosis problem to socio-economically deprived segments of the urban population, and behavioural changes causing delay in case-finding.

摘要

目的

观察日本结核病的近期流行病学趋势,并确定与发病率和死亡率恶化趋势相关的因素。

设计

按年龄、性别、年份和出生队列对结核病报告率和死亡率进行描述性分析。

结果

自1980年左右以来,结核病报告率的下降开始放缓。在1950年以前出生的队列中,自1980年左右以来,按年龄划分的报告率趋势已趋于平稳。结核病死亡率的下降最近也开始放缓,但比报告率的放缓时间更晚且程度更小。尽管结核病死亡大多发生在老年人中,但中年男性的死亡率下降速度最近有所放缓。出生队列的死亡率趋势最近随年龄呈上升趋势。

结论

目前报告率下降停滞的主要原因是过去结核病感染患病率高的老年人口增加,他们在接近生物衰老时更易发病。其他可能原因是结核病问题逐渐转向城市社会经济贫困群体,以及行为变化导致病例发现延迟。

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