Kaćaki J, Budimir M, Berović Z
Rheumatology. 1975;6:72-9.
Phytohaemagglutinin (PHA) skin test was used for screening of non-specific cell-mediated immunity in 30 patients with rheumatoid arthritis (RA) and its results compared with those obtained in age- and sex-matched controls with non-inflammatory rheumatic diseases. Purified protein derivative (PPD) of M. tuberculosis was used for testing of specific cell-mediated immunity in the same two groups. The reactivity to both PHA and PPD was found to be significantly lower in patients with RA, indicating the decreased cell-mediated immunity in this disease, as compared to controls.
采用植物血凝素（PHA）皮肤试验对30例类风湿关节炎（RA）患者的非特异性细胞介导免疫进行筛查，并将结果与年龄和性别匹配的非炎性风湿性疾病对照组的结果进行比较。两组均采用结核分枝杆菌纯蛋白衍生物（PPD）检测特异性细胞介导免疫。结果发现，RA患者对PHA和PPD的反应性均显著低于对照组，表明与对照组相比，该疾病的细胞介导免疫降低。
