Raman Steven S, Lu David S K, Kadell Barbara M, Vodopich Darko J, Sayre James, Cryer Henry
Department of Radiology, UCLA Center for the Health Sciences, 10833 Le Conte Ave., Los Angeles, CA 90095-1721, USA.
AJR Am J Roentgenol. 2002 Jun;178(6):1319-25. doi: 10.2214/ajr.178.6.1781319.
The clinical usefulness of routine, nonfocused helical CT was evaluated in diagnosing acute appendicitis or providing an alternative diagnosis in patients presenting to the emergency department with acute lower abdominal pain.
We reviewed CT reports and clinical records of 650 consecutive adult patients who presented between January 1996 and December 2000 with right lower quadrant pain or lower abdominal pain and clinical findings suggestive of appendicitis. Helical CT was performed with oral contrast material in 610 cases (93.8%) and IV contrast in 572 cases (88.0%). Both vascular and enteric contrast media were administered in 544 cases (83.7%). Rectal contrast material was administered in 52 cases (8.0%). The abdomen was helically scanned from the dome of the diaphragm to the iliac crests with a collimation of 7 mm, from the iliac crests to the acetabular roof at a 5-mm collimation, from the acetabular roof to the symphysis pubis with a collimation of 5-10 mm. The surgical or clinical record was used for follow-up.
Of the 650 patients, 552 (84.9%) had adequate clinical follow-up. There were 137 true-positive, eight false-positive, five false-negative, and 402 true-negative cases. The sensitivity, specificity, and accuracy of nonfocused helical CT were 96.5%, 98.0%, 97.6%, respectively. The positive and negative predictive values were 94.5% and 98.8%, respectively. In patients without acute appendicitis, CT suggested an alternative diagnosis, which clinically explained the patient's acute abdominal pain in 266 patients (66.2%).
Nonfocused helical CT was highly accurate in diagnosing acute appendicitis or suggesting an alternative diagnosis in patients with acute lower abdominal pain or right lower quadrant pain.
评估常规非聚焦螺旋CT在诊断急性阑尾炎或为因急性下腹痛就诊于急诊科的患者提供替代诊断方面的临床实用性。
我们回顾了1996年1月至2000年12月期间连续就诊的650例成年患者的CT报告和临床记录,这些患者表现为右下腹疼痛或下腹痛且临床检查结果提示阑尾炎。610例(93.8%)患者进行螺旋CT检查时口服了对比剂,572例(88.0%)静脉注射了对比剂。544例(83.7%)患者同时使用了血管和肠道对比剂。52例(8.0%)患者直肠注入了对比剂。腹部扫描范围从膈顶至髂嵴,准直为7mm;从髂嵴至髋臼顶,准直为5mm;从髋臼顶至耻骨联合,准直为5 - 10mm。采用手术或临床记录进行随访。
650例患者中,552例(84.9%)获得了充分的临床随访。其中真阳性137例,假阳性8例,假阴性5例,真阴性402例。非聚焦螺旋CT的敏感性、特异性和准确性分别为96.5%、98.0%、97.6%。阳性预测值和阴性预测值分别为94.5%和98.8%。在无急性阑尾炎的患者中,CT提示了替代诊断,在266例患者(66.2%)中从临床角度解释了患者的急性腹痛。
非聚焦螺旋CT在诊断急性阑尾炎或为急性下腹痛或右下腹疼痛患者提示替代诊断方面具有高度准确性。