乳糜泻患者空肠液中的抗网硬蛋白抗体
Anti-reticulin antibody in jejunal juice in coeliac disease.
作者信息
Mawhinney H, Love A H
出版信息
Clin Exp Immunol. 1975 Sep;21(3):394-8.
Abstract
Anti-reticulin antibody has been demonstrated in the jejunal juice of eight out of fourteen (57%) untreated coeliac patients, one out of twelve (8%) patients with normal jejunal biopsies and none of ten normal control subjects. The jejunal juice antibody was invariably of the IgA class. It is suggested that the presence of anti-reticulin antibody in the jejunal juice in coeliac disease supports the hypothesis that this antibody is secreted in response to reticulin antigens present in the diet.
摘要
在14名未经治疗的乳糜泻患者中，有8名（57%）的空肠液中检测到抗网硬蛋白抗体；12名空肠活检正常的患者中有1名（8%）检测到该抗体；而10名正常对照者中均未检测到。空肠液中的抗体均为IgA类。提示乳糜泻患者空肠液中抗网硬蛋白抗体的存在支持了这样一种假说，即该抗体是针对饮食中存在的网硬蛋白抗原分泌产生的。
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