复杂性状遗传学：多变量策略的出现
Complex-trait genetics: emergence of multivariate strategies.
作者信息
Phillips Tamara J, Belknap John K
机构信息
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR 97201, USA.
出版信息
Nat Rev Neurosci. 2002 Jun;3(6):478-85. doi: 10.1038/nrn847.
DOI:10.1038/nrn847
PMID:12042883
Abstract
Complex traits, including many disease-related traits, are influenced by multiple genes. Bivariate approaches that associate one gene with one trait are yielding to multivariate methods to synthesize the effects of multiple genes, integrate results across independent studies, and aid in the identification of coordinated pathways and interactions between loci.
摘要
复杂性状，包括许多与疾病相关的性状，受多个基因影响。将一个基因与一个性状相关联的双变量方法正让位于多变量方法，以综合多个基因的效应、整合独立研究的结果，并有助于识别基因座之间的协同通路和相互作用。
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