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人体肌腱组织的形态功能变化

Morpho-functional changes in human tendon tissue.

作者信息

Galliani I, Burattini S, Mariani A R, Riccio M, Cassiani G, Falcieri E

机构信息

Department of Human Anatomy, University of Bologna, Italy.

出版信息

Eur J Histochem. 2002;46(1):3-12. doi: 10.4081/1649.

DOI:10.4081/1649
PMID:12044045
Abstract

Insertion tissue biopsies of right arm common extensor tendons from 11 patients with chronic lateral epicondylitis were processed for light and electron microscopy. The subjects were aged between 38 and 54 years (only one was 25). The specimens showed a variety of structural changes such as biochemical and spatial alteration of collagen, hyaline degeneration, loss of tenocytes, fibrocartilage metaplasia, calcifying processes, neovascularization and vessel wall modifications. Tissue alterations were evident in limited zones of the tendon fibrocartilage in which the surgical resection was generally visible. The areas where the degenerative processes were localized, were restricted and in spatial contiguity with morphologically normal ones. The observed cases presented histological and electron microscopic findings that characterize lateral epicondylitis as a degenerative phenomenon involving all tendon components.

摘要

对11例慢性外侧上髁炎患者右臂常见伸肌腱进行插入组织活检,用于光镜和电镜检查。受试者年龄在38至54岁之间(仅1例为25岁)。标本显示出多种结构变化,如胶原蛋白的生化和空间改变、玻璃样变性、腱细胞丢失、纤维软骨化生、钙化过程、新生血管形成和血管壁改变。组织改变在肌腱纤维软骨的有限区域明显,手术切除部位通常可见。退行性变过程所在区域受限,且与形态正常的区域在空间上相邻。观察到的病例呈现出组织学和电子显微镜检查结果,这些结果将外侧上髁炎表征为一种涉及所有肌腱成分的退行性现象。

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