Shirai A, Chan T C, Gan E, Huxsoll D L
Jpn J Med Sci Biol. 1979 Jun;32(3):179-84. doi: 10.7883/yoken1952.32.179.
The persistence of R. tsutsugamushi in tissues of experimentally infected mice for 565 days was demonstrated. Reactivation of apparently dormant infections was accomplished by inoculating the mice with a heterologous strain of the organism or treatment with cyclophosphamide.
已证实恙虫病东方体在实验感染小鼠组织中可存活565天。通过给小鼠接种该病原体的异源菌株或用环磷酰胺治疗,可使明显潜伏的感染重新激活。