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酿酒酵母中的上位性和杂种不育

Epistasis and hybrid sterility in Saccharomyces.

作者信息

Greig Duncan, Borts Rhona H, Louis Edward J, Travisano Michael

机构信息

The Galton Laboratory, Department of Biology, University College London, Gower Street, UK.

出版信息

Proc Biol Sci. 2002 Jun 7;269(1496):1167-71. doi: 10.1098/rspb.2002.1989.

Abstract

Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.

摘要

杂种不育被认为是由于来自不同物种的基因之间有害的上位相互作用所致。在此,我们证明显性基因不相容性对酿酒酵母与五个近缘物种之间杂种的不育性没有影响。通过基因组加倍使不育二倍体变为可育,从而产生杂种四倍体。基于这些以及先前的结果,我们得出结论,基因不相容性和经典的染色体物种形成模型均不适用。

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