Margolis David J, Bilker Warren, Knauss Jill, Baumgarten Mona, Strom Brian L
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Ann Epidemiol. 2002 Jul;12(5):321-5. doi: 10.1016/s1047-2797(01)00255-1.
The objective of this study was to estimate the period prevalence and incidence of pressure ulcer among those 65 years of age and older.
We used a patient-record database called the General Practice Research Database (GPRD). Subjects were 65 years of age and older and cases were ascertained based on strict inclusion and exclusion criteria. The accuracy of the ascertainment strategy was estimated using mailed physician-answered questionnaires. Annual period prevalence and age-specific incidence were estimated per 100 person-years with exact 95% confidence intervals (CI).
The accuracy of our ascertainment strategy was excellent, with a positive predictive value of 100% (95% CI: 92%,100%) and negative predictive value of 95% (85%, 95%). Over 200,000 person-years of data were analyzed. The annual period prevalence of pressure ulcer among those 65 years of age and older varied from 0.31% to 0.70%. The incidence varied significantly with advancing patient age from 0.18 to 3.36 per 100-person years (p < 0.001) but was not associated with gender (p = 0.95).
Pressure ulcers are seen in the general practice setting. They are most likely to occur in those over 85 years of age. Preventative strategies within the general practice setting should concentrate on the oldest of the elderly.
本研究的目的是估计65岁及以上人群中压疮的期间患病率和发病率。
我们使用了一个名为全科医疗研究数据库(GPRD)的患者记录数据库。研究对象为65岁及以上人群,病例根据严格的纳入和排除标准确定。使用邮寄的医生回答问卷来估计确定策略的准确性。每100人年估计年度期间患病率和特定年龄发病率,并给出精确的95%置信区间(CI)。
我们的确定策略准确性极佳,阳性预测值为100%(95%CI:92%,100%),阴性预测值为95%(85%,95%)。分析了超过200,000人年的数据。65岁及以上人群中压疮的年度期间患病率在0.31%至0.70%之间。发病率随患者年龄增长显著变化,每100人年从0.18至3.36(p < 0.001),但与性别无关(p = 0.95)。
在全科医疗环境中可见压疮。它们最有可能发生在85岁以上的人群中。全科医疗环境中的预防策略应集中于最年长的老年人。