Heuschmid M, Küttner A, Flohr T, Wildberger J E, Lell M, Kopp A F, Schröder S, Baum U, Schaller S, Hartung A, Ohnesorge B, Claussen C D
Abteilung Radiologische Diagnostik, Universitätsklinikum Tübingen, Germany.
Rofo. 2002 Jun;174(6):721-4. doi: 10.1055/s-2002-32227.
First evaluation of image quality of a new 16-slice multidetector-row computed tomography (MDCT) for the assessment of coronary artery disease and lesion detection of the coronary arteries.
On a newly developed 16-slice CT scanner (SOMATOM Sensation 16, Siemens, Forchheim, Germany) a calcium score as well as a contrast-enhanced CT angiography (CTA) were performed on 4 patients with retrospective ECG-gating and a gantry rotation time of 420 ms to exclude or follow-up coronary heart disease. CTA was performed after injecting 120 ml contrast media intravenously. After medication with a ss-Blocker, the heart rate was between 55 and 67 bpm.
The scan time for calcium score was 12 s, for CTA 18 s (scan range 15 and 12 cm, respectively). Volume score was between 0 and 256.4. In the CT angiography the entire coronary tree could be visualized in all patients up to the very distal subsegmental branches. In two patients a complete occlusion of the RCA and the LAD were depicted, respectively. In one of these patients, a large aneurysm of the left anterior ventricular wall was also delineated.
Considering our first experiences with the new 16-slice technology, an excellent visualization of the entire coronary tree including the very distal and side branches due to substantially increased spatial resolution seems to be achievable. In these patients the acquired image quality raises the hope for improved, non-invasive cardiac diagnostics. In larger studies, the clinical impact of this new technology needs to be further investigated.
首次评估一种新型16层多排螺旋计算机断层扫描(MDCT)用于评估冠状动脉疾病及检测冠状动脉病变的图像质量。
在一台新开发的16层CT扫描仪(西门子公司的SOMATOM Sensation 16,德国福希海姆)上,对4例患者进行回顾性心电门控,机架旋转时间为420毫秒,进行钙化积分以及对比增强CT血管造影(CTA),以排除或随访冠心病。静脉注射120毫升造影剂后进行CTA。服用β受体阻滞剂后,心率在55至67次/分钟之间。
钙化积分扫描时间为12秒,CTA为18秒(扫描范围分别为15厘米和12厘米)。容积积分在0至256.4之间。在CT血管造影中,所有患者的整个冠状动脉树直至最远端的亚节段分支均可显示。在两名患者中,分别显示了右冠状动脉(RCA)和左前降支(LAD)的完全闭塞。在其中一名患者中,还发现了左心室前壁的一个大动脉瘤。
鉴于我们对新16层技术的初步经验,由于空间分辨率大幅提高,似乎可以实现对整个冠状动脉树包括最远端和侧支的极佳显示。在这些患者中,所获得的图像质量为改进无创心脏诊断带来了希望。在更大规模的研究中,需要进一步研究这项新技术的临床影响。