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GLC determination of carbamazepine suitable for pharmacokinetic studies.

作者信息

Gérardin A, Abadie F, Laffont J

出版信息

J Pharm Sci. 1975 Dec;64(12):1940-2. doi: 10.1002/jps.2600641206.

DOI:10.1002/jps.2600641206
PMID:1206485
Abstract

A GLC determination of carbamazepine in plasma and urine is described. It is performed by injecting the cyano derivative, which, in contrast to carbamazepine, has bood GLC properties. The method is suitable for pharmacokinetic studies, since it is specific and accurate down to 0.27 mug/ml.

摘要

相似文献

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GLC determination of carbamazepine suitable for pharmacokinetic studies.
J Pharm Sci. 1975 Dec;64(12):1940-2. doi: 10.1002/jps.2600641206.
2
Simultaneous determination of carbamazepine and its epoxide metabolite in plasma and urine by high-performance liquid chromatography.
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Routine monitoring of carbamazepine and carbamazepine-10,11-epoxide in plasma by high-performance liquid chromatography using 10-methoxycarbamazepine as internal standard.以10-甲氧基卡马西平为内标,采用高效液相色谱法对血浆中的卡马西平和卡马西平-10,11-环氧化物进行常规监测。
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GLC analysis of carbamazepine.卡马西平的气相色谱分析
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引用本文的文献

1
Pharmacokinetics of carbamazepine in normal humans after single and repeated oral doses.卡马西平单次及多次口服给药后在正常人体内的药代动力学
J Pharmacokinet Biopharm. 1976 Dec;4(6):521-35. doi: 10.1007/BF01064556.