Sasaki Eisuke, Yamanouchi Hirotsugu, Shioshita Kei, Hayakawa Tomoichiro, Izumikawa Koichi, Izumikawa Kinichi, Hara Kohei, Hirakata Yoichi, Kohno Shigeru
Izumikawa Hospital, Department of Laboratory Medicine, Nagasaki University School of Medicine.
Kansenshogaku Zasshi. 2002 May;76(5):391-5. doi: 10.11150/kansenshogakuzasshi1970.76.391.
A 65-year-old male patient with a history of alcoholism visited our outpatient clinic complaining of nausea and diarrhea followed by dizziness. Erythema and swelling with partial exfoliation on the right forearm to hand and right thigh were noticed. Vibrio vulnificus was isolated from the purulent discharge of the skin. Due to urgent and intensive treatment of bacterial shock and antimicrobial drugs, the patient fully recovered three months later. We believe that the patient survived from this fatal infection because; 1) the isolates were highly sensitive to a wide variety of antibiotics, 2) the antibiotic therapy was started immediately, with an alternative usage of different antibiotics, and 3) the liver dysfunction of the patient had not been severely damaged by alcohol before the infection.
一名有酗酒史的65岁男性患者到我们门诊就诊,主诉先是恶心、腹泻,随后出现头晕。发现其右前臂至手部及右大腿有红斑、肿胀并伴有部分脱皮。从皮肤脓性分泌物中分离出创伤弧菌。由于对细菌性休克进行了紧急强化治疗并使用了抗菌药物,患者在三个月后完全康复。我们认为该患者能从这种致命感染中存活下来的原因是:1)分离出的菌株对多种抗生素高度敏感;2)立即开始抗生素治疗,并交替使用不同抗生素;3)患者的肝功能在感染前未因酒精而受到严重损害。