Gábor K, András S, Barnabás L, László B, Iván H
Morphol Igazsagugyi Orv Sz. 1975 Jul;15(3):161-5.
After an acute HbsAg-positive transfusion hepatitis the patient--a 40 years old women--remained seropositive. Later a chronic aggressive hepatitis have developed, which could be evidenced by histological findings. On the electron microphage in the nucleus of liver cells ring-shaped particules 20--25 nm in diameter were revealed. They consisted of granula 2--3 nm in diameter. These particules are considered to represent so called virus-nuclei (core of the virus B of hepatitis) and to play a pathogenic role. These particules are commonly present and easily found. The great number of them--according to author's opinion--can be explained by the effect of immunosuppressive therapy.
一名40岁女性患者在发生急性乙肝表面抗原阳性输血后肝炎后仍血清学阳性。后来发展为慢性侵袭性肝炎，这可通过组织学检查结果得到证实。在电子显微镜下，肝细胞细胞核中发现了直径为20 - 25纳米的环形颗粒。它们由直径为2 - 3纳米的颗粒组成。这些颗粒被认为代表所谓的病毒核（乙型肝炎病毒的核心）并发挥致病作用。这些颗粒普遍存在且易于发现。据作者认为，它们数量众多可通过免疫抑制治疗的作用来解释。
