Morgan Melinda, Rapkin Andrea
Department of Adult Psychiatry, University of California, Los Angeles, USA.
J Gend Specif Med. 2002 May-Jun;5(3):28-36.
To evaluate cognitive functioning throughout the menstrual cycle in women who suffer from premenstrual dysphoric disorder (PDD) and controls. RESEARCH HYPOTHESIS: Measures of cognitive function will discriminate between women with prospectively documented PDD and women without PDD during the late-luteal phase of the menstrual cycle.
The participants consisted of 37 women who met operationalized, prospectively documented criteria of premenstrual dysphoric disorder and 32 women without PDD who served as controls.
A series of neurocognitive tasks were used to assess selective, sustained attention, reaction time, and cognitive flexibility in women with PDD and controls. Tests were administered on two occasions: once during the follicular phase of the menstrual cycle, and once during the late-luteal phase.
Repeated measures and discriminant analyses failed to demonstrate significant group differences between women with PDD and controls in neurocognitive functioning.
The findings indicated that cognitive functioning in the late-luteal phase was not compromised in either group, in spite of subjective reports from the PDD group. The findings suggest that complaints of cognitive dysfunction may be mediated by altered perceptions and sociocultural expectations rather than by identifiable cognitive deficits.
评估患有经前烦躁障碍（PDD）的女性和对照组女性在整个月经周期中的认知功能。研究假设：在月经周期的黄体晚期，认知功能测量将区分有前瞻性记录的PDD女性和无PDD女性。
参与者包括37名符合经前烦躁障碍操作性前瞻性记录标准的女性和32名无PDD的女性作为对照。
使用一系列神经认知任务来评估PDD女性和对照组女性的选择性、持续注意力、反应时间和认知灵活性。测试在两个时间段进行：一次在月经周期的卵泡期，一次在黄体晚期。
重复测量和判别分析未能显示PDD女性和对照组在神经认知功能上有显著的组间差异。
研究结果表明，尽管PDD组有主观报告，但两组在黄体晚期的认知功能均未受损。研究结果表明，认知功能障碍的主诉可能是由感知改变和社会文化期望介导的，而非由可识别的认知缺陷所致。
