1例罕见的溃疡性结肠炎合并威尔逊病病例：两种疾病之间可能存在关联。
A rare case of ulcerative colitis complicating Wilson's disease: possible association between the two diseases.
作者信息
Torisu Takahiro, Esaki Motohiro, Matsumoto Takayuki, Nakamura Shotaro, Azuma Koichi, Okada Mitsuo, Tsuji Hiroshi, Yao Takashi, Iida Mitsuo
机构信息
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
出版信息
J Clin Gastroenterol. 2002 Jul;35(1):43-5. doi: 10.1097/00004836-200207000-00010.
A case of ulcerative colitis complicated by Wilson's disease is described. In this case, ulcerative colitis occurred 12 years after the diagnosis of Wilson's disease, and the colitis was intractable to prednisolone and salazosulfapyridine. Because copper is one of the trace elements necessary for antioxidant defenses during inflammatory process, altered copper metabolism may have contributed to the intractability of the ulcerative colitis in this case.
本文描述了一例溃疡性结肠炎合并威尔逊病的病例。在该病例中，溃疡性结肠炎在威尔逊病诊断12年后出现，且对泼尼松龙和柳氮磺胺吡啶治疗无效。由于铜是炎症过程中抗氧化防御所需的微量元素之一，铜代谢改变可能导致了该病例中溃疡性结肠炎的难治性。
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