Mouridsen Svend Erik, Rich Bente, Isager Torben
Department of Child and Adolescent Psychiatry, Bispebjerg Hospital, Copenhagen, Denmark.
Autism. 2002 Jun;6(2):197-205. doi: 10.1177/1362361302006002006.
Morphometry, the measurement of forms, is an ancient practice. Recently, evidence has grown to support the notion that aberrant neurodevelopment may play a role in the pathophysiology of autism. Is the body, like the brain, affected by abnormal development in these patients? The aim of this study was to evaluate body mass index (BMI) of children with infantile autism, by comparing the BMI of 117 children with infantile autism with the corresponding BMI percentiles in an age- and sex-matched reference population. The BMI distribution of the male, but not female, children with infantile autism was significantly lower than that of the age-matched reference population. There was no evidence that BMI was associated with intelligence or socioeconomic status among children with infantile autism.
形态测量学,即对形态的测量,是一种古老的做法。最近,越来越多的证据支持这样一种观点,即异常的神经发育可能在自闭症的病理生理学中起作用。在这些患者中,身体是否像大脑一样受到异常发育的影响?本研究的目的是通过比较117名婴儿期自闭症儿童的体重指数(BMI)与年龄和性别匹配的参考人群中的相应BMI百分位数,来评估婴儿期自闭症儿童的BMI。婴儿期自闭症男性儿童的BMI分布显著低于年龄匹配的参考人群,而女性儿童则不然。没有证据表明婴儿期自闭症儿童的BMI与智力或社会经济地位有关。