Korenromp E L, Bakker R, Gray R, Wawer M J, Serwadda D, Habbema J D F
Erasmus University Rotterdam, Department of Public Health, The Netherlands.
Sex Transm Infect. 2002 Apr;78 Suppl 1(Suppl 1):i55-63. doi: 10.1136/sti.78.suppl_1.i55.
An assessment was made of how the HIV epidemic may have influenced sexually transmitted disease (STD) epidemiology in Uganda, and how HIV would affect the effectiveness of syndromic STD treatment programmes during different stages of the epidemic. The dynamic transmission model STDSIM was used to simulate the spread of HIV and four bacterial and one viral STD. Model parameters were quantified using demographic, behavioural, and epidemiological data from rural Rakai and other Ugandan populations. The findings suggest that severe HIV epidemics can markedly alter STD epidemiology, especially if accompanied by a behavioural response. Likely declines in bacterial causes of genital ulcers should be considered in defining policies on syndromic STD management in severe HIV epidemics.
评估了艾滋病毒疫情可能如何影响乌干达的性传播疾病（STD）流行病学，以及艾滋病毒在疫情不同阶段将如何影响症状性STD治疗方案的有效性。使用动态传播模型STDSIM来模拟艾滋病毒以及四种细菌性和一种病毒性STD的传播。利用来自拉凯农村地区和乌干达其他人群的人口统计学、行为学和流行病学数据对模型参数进行了量化。研究结果表明，严重的艾滋病毒疫情可显著改变STD流行病学，尤其是在伴有行为反应的情况下。在制定严重艾滋病毒疫情下症状性STD管理政策时，应考虑到生殖器溃疡细菌性病因可能的下降情况。
