Ahrendt Steven A, Pitt Henry A
Department of Surgery, University of Rochester, New York, USA.
Oncology (Williston Park). 2002 Jun;16(6):725-34; discussion 734, 736-8, 740, 743.
Pancreatic cancer is the fifth leading cause of cancer death in the United States, with an overall survival rate of 3%. Unfortunately, only a minority of patients present with localized disease amenable to surgical resection. Over the past 20 years, improvements in operative and perioperative management have led to a decrease in operative mortality, shorter hospital stay, and overall 5-year survival of approximately 20% in patients undergoing pancreaticoduodenectomy. Despite advances in nonoperative palliation, surgery continues to play an important role in the management of patients with locally advanced, unresectable pancreatic cancer.
胰腺癌是美国癌症死亡的第五大主要原因，总体生存率为3%。不幸的是，只有少数患者表现为适合手术切除的局限性疾病。在过去20年中，手术及围手术期管理的改善已导致手术死亡率降低、住院时间缩短，并且接受胰十二指肠切除术的患者总体5年生存率约为20%。尽管非手术姑息治疗取得了进展，但手术在局部晚期、无法切除的胰腺癌患者的管理中仍继续发挥重要作用。
