Awano S, Gohara K, Kurihara E, Ansai T, Takehara T
Department of Preventive Dentistry, Kyushu Dental College, Kitakyushu, Japan.
Int Dent J. 2002 Jun;52 Suppl 3:212-6. doi: 10.1002/j.1875-595x.2002.tb00927.x.
To evaluate the association between the presence of periodontal pathogenic bacteria in saliva and halitosis in mouth air.
Cross-sectional microbiological and clinical oral examination of adult patients.
101 adult patients (25 males, 76 females) who attended the Preventive Dentistry and Breath Odour Clinic of Kyushu Dental College. Their average age was 50.0+/-13.5 years old (mean +/- SD).
The subjects were classified into three groups: halitosis subjects with a probing depth (PD) > or = 4mm (P group), halitosis subjects without PD > or = 4mm (H group), and non-halitosis subjects without PD > or = 4mm (C group).
All subjects received a periodontal examination. Volatile sulphur compounds (VSC: hydrogen sulphide and methyl mercaptan) were measured using gas chromatography. The presence of Bacteroides forsythus, Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Prevotella intermedia in the saliva was detected by polymerase chain reaction.
The presence of B. forsythus, P. gingivalis and P. intermedia influenced the production of VSC. Specifically, the presence of B. forsythus in subjects with periodontitis was strongly correlated to the concentration of VSC in mouth air.
评估唾液中牙周病原菌的存在与口腔口气中口臭之间的关联。
对成年患者进行横断面微生物学和临床口腔检查。
101名成年患者（25名男性，76名女性），他们前往九州牙科大学预防牙科与口臭诊所就诊。他们的平均年龄为50.0±13.5岁（平均值±标准差）。
将研究对象分为三组：探诊深度（PD）≥4mm的口臭患者（P组）、PD＜4mm的口臭患者（H组）以及PD＜4mm的无口臭患者（C组）。
所有研究对象均接受牙周检查。使用气相色谱法测量挥发性硫化物（VSC：硫化氢和甲硫醇）。通过聚合酶链反应检测唾液中福赛坦氏菌、牙龈卟啉单胞菌、伴放线放线杆菌和中间普氏菌的存在情况。
福赛坦氏菌、牙龈卟啉单胞菌和中间普氏菌的存在会影响VSC的产生。具体而言，牙周炎患者中福赛坦氏菌的存在与口腔口气中VSC的浓度密切相关。
