Mottram Philip M, Gelman John S
Centre for Heart and Chest Research, Monash Medical Centre, Clayton, Melbourne, Victoria, Australia.
J Am Soc Echocardiogr. 2002 Jul;15(7):746-8. doi: 10.1067/mje.2002.118914.
Cardiac valvular abnormalities detected by echocardiography are relatively common in patients with the primary antiphospholipid syndrome. Valvular thickening with small vegetations are typical, but reports of lesion histology are rare. We report the case of a 50-year-old man presenting with thromboembolic phenomena who had a large (>2 cm), mobile, pedunculated, mass attached to the mitral valve that had the echocardiographic appearance of a primary valve tumor. Following surgical removal, histopathologic examination demonstrated pure fibrin thrombus and serological testing confirmed the antiphospholipid syndrome. This case highlights an unusual echocardiographic appearance of intracardiac thrombus in this syndrome.
经超声心动图检测发现，心脏瓣膜异常在原发性抗磷脂综合征患者中相对常见。瓣膜增厚伴小赘生物是典型表现，但关于病变组织学的报道很少。我们报告一例50岁男性患者，其出现血栓栓塞现象，二尖瓣上附着一个大的（>2 cm）、可移动的、有蒂的肿块，超声心动图表现为原发性瓣膜肿瘤。手术切除后，组织病理学检查显示为单纯纤维蛋白血栓，血清学检测证实为抗磷脂综合征。该病例突出了此综合征中心腔内血栓一种不寻常的超声心动图表现。
