Yuan Shi-Min, Jing Hua, Lavee Jacob
Department of Cardiac and Thoracic Surgery, The Chaim Sheba Medical Center, Tel Hashomer Israel;
Rare Tumors. 2009 Dec 28;1(2):e35. doi: 10.4081/rt.2009.e35.
Valvular tumors and tumor-like lesions may have similar morphological and clinical characteristics, and may place the patients at a high risk of stroke in different ways. From January 2004 to June 2008, 11 patients underwent surgery for a suspected valvular tumor. Valvular tumor and tumor-like lesions accounted for 0.32% of adult cardiac operations. Five (45.5%) valvular lesions were papillary fibroelastomas, one (9.1%) was myxoma, 2 (18.2%) were organized thrombi, and 3 (27.3%) were calcification lesions. There was a total of 5 (45.5%) atrioventricular valve lesions, 4 arising from the atrial side of the leaflets, and one from the ventricular side. All 5 (45.5%) semilunar valvular lesions were from the aortic valve. One (9.1%) lesion originated from the chorda tendinea of the mitral valve. All leaflet lesions were resected by a simple shave technique, and all the patients recovered favorably. Valvular tumor and tumor-like lesions are rare. Pre-operative differential diagnoses among these valvular lesions pose important clinical implications for appropriate treatment for the underlying diseases. Prompt therapeutic measures in view of the underlying diseases of the valvular lesions are essential to prevent potential embolic events.
心脏瓣膜肿瘤及肿瘤样病变可能具有相似的形态学和临床特征，并可能以不同方式使患者处于中风的高风险中。2004年1月至2008年6月，11例疑似心脏瓣膜肿瘤患者接受了手术。心脏瓣膜肿瘤及肿瘤样病变占成人心脏手术的0.32%。5例（45.5%）瓣膜病变为乳头状纤维弹性瘤，1例（9.1%）为黏液瘤，2例（18.2%）为机化血栓，3例（27.3%）为钙化病变。共有5例（45.5%）房室瓣病变，4例起源于瓣叶心房侧，1例起源于心室侧。所有5例（45.5%）半月瓣病变均来自主动脉瓣。1例（9.1%）病变起源于二尖瓣腱索。所有瓣叶病变均采用简单的刮除技术切除，所有患者恢复良好。心脏瓣膜肿瘤及肿瘤样病变较为罕见。这些瓣膜病变的术前鉴别诊断对基础疾病的恰当治疗具有重要临床意义。鉴于瓣膜病变的基础疾病采取及时的治疗措施对于预防潜在的栓塞事件至关重要。
