Galagan N P, Korotkoruchko V P
Ukr Biokhim Zh. 1975 Mar-Apr;47(2):169-71.
The activity of reconstructed glyceraldehyde phosphate dehydrogenase and lactate dehydrogenase reactions was studied as affected by immunoglobulin G of blood serum from patients with cancer and protein positively reacting in sedimentation test for cancer which is one of its subfractions. Addition of the protein under study to the sample is shown to inhibit the glyceraldehyde phosphate dehydrogenase reaction but activates the lactate dehydrogenase one. On the basis of the data obtained a conclusion is made that the effect of immunoglobulins G in the glycolytic systems is connected with the reactions of hydrogen transfer.
研究了重构的磷酸甘油醛脱氢酶和乳酸脱氢酶反应的活性，其受癌症患者血清免疫球蛋白G以及在癌症沉淀试验中呈阳性反应的蛋白质（该蛋白质是其亚组分之一）的影响。结果表明，将所研究的蛋白质添加到样品中会抑制磷酸甘油醛脱氢酶反应，但会激活乳酸脱氢酶反应。基于所获得的数据得出结论，免疫球蛋白G在糖酵解系统中的作用与氢转移反应有关。
