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[纤维肌痛——最新进展]

[Fibromyalgia--an update].

作者信息

Wigers Sigrid Hørven

机构信息

Opptreningssenteret Jeløy Kurbad Bråtengata 94 1515 Moss.

出版信息

Tidsskr Nor Laegeforen. 2002 May 20;122(13):1300-4.

Abstract

BACKGROUND

Fibromyalgia is a common, female dominated condition, characterized by chronic widespread pain, fatigue, sleep disturbance, anxiety/depression and a number of other symptoms. The syndrome's aetiology and treatment is disputed. However, research over the last decade has provided substantial new information.

MATERIAL AND METHODS

This review is an update on fibromyalgia with respect to predictors, pathogenesis and treatment. On the basis of a number of important scientific publications, the most relevant theory is presented and discussed.

RESULTS

Fibromyalgia may be described as a biopsychosocial disorder in which long lasting distress, myofascial pain, central sensitisation, sickness behaviour, anxiety/depression, neuroendocrine and autonomic dysfunction play central aetiological roles as elements in a vicious circle. Treatment should be focused on each of these elements and requires active patient participation. It is best given as a multidimensional, multidisciplinary rehabilitation programme with continuous support from the general practitioner.

INTERPRETATION

Even though the fibromyalgia riddle is not yet fully solved, research over the last decade has given valuable new information on pathogenesis and treatment. We should be able to offer our patients substantial help on the basis of present knowledge.

摘要

背景

纤维肌痛是一种常见的、以女性为主的病症,其特征为慢性广泛性疼痛、疲劳、睡眠障碍、焦虑/抑郁以及许多其他症状。该综合征的病因和治疗方法存在争议。然而,过去十年的研究提供了大量新信息。

材料与方法

本综述是关于纤维肌痛在预测因素、发病机制和治疗方面的更新。基于一些重要的科学出版物,提出并讨论了最相关的理论。

结果

纤维肌痛可被描述为一种生物心理社会障碍,其中长期的痛苦、肌筋膜疼痛、中枢敏化、疾病行为、焦虑/抑郁、神经内分泌和自主神经功能障碍在恶性循环中作为病因要素发挥核心作用。治疗应针对这些要素中的每一个,并且需要患者积极参与。最好作为一个多维度、多学科的康复计划进行,由全科医生持续提供支持。

解读

尽管纤维肌痛之谜尚未完全解开,但过去十年的研究已在发病机制和治疗方面给出了有价值的新信息。基于目前的知识,我们应该能够为患者提供实质性的帮助。

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