Monforte M T, Trovato A, Rossitto A, Forestieri A M, D'Aquino A, Miceli N, Galati E M
Pharmaco-Biological Department, School of Pharmacy, University of Messina, Vill. SS. Annunziata, 98168 Messina, Italy.
Phytother Res. 2002 Jun;16(4):395-7. doi: 10.1002/ptr.977.
The effect of Salvadora persica L. stem extracts on the potentiation of sodium pentobarbital activity and on generalized tonic-clonic seizure produced by pentylenetetrazol (PTZ) on the rat is reported. The extracts of Salvadora persica L. extended sleeping-time and decreased induction-time induced by sodium pentobarbital; in addition it showed protection against pentylenetetrazol-induced convulsion by increasing the latency period and diminishing the death rate.
据报道,桃金娘科没药树茎提取物对戊巴比妥钠活性增强以及对大鼠戊四氮(PTZ)诱发的全身强直性阵挛性惊厥的影响。桃金娘科没药树提取物延长了戊巴比妥钠诱导的睡眠时间并缩短了诱导时间;此外,它通过延长潜伏期和降低死亡率,对戊四氮诱发的惊厥表现出保护作用。