Rezaei Sahra, Rezaei Korosh, Mahboubi Mohaddese, Jarahzadeh Mohammad Hossein, Momeni Ehsan, Bagherinasab Mostafa, Targhi Mehrdad Gaffari, Memarzadeh Mohammad Reza
Department of Nursing, School of Nursing and Midwifery, Arak University of Medical Sciences, Arak, Iran.
Department of Microbiology, Medicinal Plant, Research Center of Barij Essence, Kashan, Iran.
J Indian Soc Periodontol. 2016 Jul-Aug;20(4):404-408. doi: 10.4103/0972-124X.194269.
Intubated patients in Intensive Care Unit (ICU) are not able to take care of their mouth health, so they are at risk of bacterial colonization and dental plaques formation that can lead to systemic diseases such as pneumonia and gingivitis.
In randomized, double-blind clinical study, the efficacy of natural herbal mouthwash containing ethanol extract and gel was compared with chlorhexidine on gingival index (GI) of intubated patients in ICU.
Seventy-six intubated patients (18-64 years old with mean age 40.35 ± 13.2) in ICU were admitted to this study. The patients were randomly divided into two groups: (1) Herbal mouthwash and (2) chlorhexidine solution. Before the intervention, the GIs was measured by modified GI device into two groups. The mouth was rinsed by mouthwashes every 2-3 h for 4 days. 2 h after the last intervention, GIs were determined.
Along with mechanical methods, herbal mouthwash in reducing GI was statistically significant than that of chlorhexidine ( < 0.05).
The results of this study introduce a new botanical extract mouthwash with dominant healing effects on GI (1.5 ± 0.6) higher than that of synthetic mouthwash, chlorhexidine (2.31 ± 0.73).
重症监护病房(ICU)中插管患者无法自行护理口腔卫生,因此他们面临细菌定植和牙菌斑形成的风险,这可能导致肺炎和牙龈炎等全身性疾病。
在一项随机双盲临床研究中,将含有乙醇提取物和凝胶的天然草药漱口水与洗必泰对ICU插管患者牙龈指数(GI)的疗效进行比较。
本研究纳入了76名ICU插管患者(年龄18 - 64岁,平均年龄40.35±13.2岁)。患者被随机分为两组:(1)草药漱口水组和(2)洗必泰溶液组。干预前,使用改良的牙龈指数测量装置对两组患者的牙龈指数进行测量。每2 - 3小时用漱口水漱口,持续4天。最后一次干预2小时后,测定牙龈指数。
与机械方法一起,草药漱口水在降低牙龈指数方面比洗必泰具有统计学意义(<0.05)。
本研究结果推出了一种新型植物提取物漱口水,其对牙龈指数的主要愈合效果(1.5±0.6)高于合成漱口水洗必泰(2.31±0.73)。