Tamaki Y, Watanabe S, Yamada Y
Anim Blood Groups Biochem Genet. 1975;6(4):185-93. doi: 10.1111/j.1365-2052.1975.tb01363.x.
A genetic role of isozyme types in plasma alkaline phosphatase (AP) activity within dam families in the young chicken was investigated in a White Plymouth Rock strain kept in our laboratory since 1961. Plasma samples were obtained at 32 and 56 days of age and subjected to horizontal polyacrylamide gel electrophoresis and two methods of analysis. A higher level of plasma AP activity of the fast (F) type relative to that of slow (S) type was re-confirmed. The F types of full-sib chicks had distinctly higher AP activity than the S types. Also within isozyme types, family differences were significant in the F type but not in the S type. The correlation of AP activities between 32 and 56 days of age was significant in the F type but not in the S type, which could be attributed to the effect of aging. The genetic control of plasma AP activity in young chickens were discussed under a hypothesis of two independent genetic systems, i.e. major genic and polygenic.
自1961年起，我们实验室一直在饲养白普利茅斯洛克品系的鸡，在此品系中，对幼鸡亲代家系中同工酶类型在血浆碱性磷酸酶（AP）活性方面的遗传作用进行了研究。在32日龄和56日龄时采集血浆样本，并进行水平聚丙烯酰胺凝胶电泳和两种分析方法。再次证实了快速（F）型血浆AP活性水平高于慢速（S）型。全同胞雏鸡的F型AP活性明显高于S型。同样在同工酶类型中，F型的家系差异显著，而S型则不显著。32日龄和56日龄时AP活性的相关性在F型中显著，而在S型中不显著，这可能归因于衰老的影响。在两个独立遗传系统，即主基因和多基因的假设下，讨论了幼鸡血浆AP活性的遗传控制。
