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2
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本文引用的文献

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[Encephalomyelitis listeriaca apostematosa].[李斯特菌性脓肿性脑脊髓炎]
Schweiz Med Wochenschr. 1957 Mar 2;87(9):210-4.
2
Evidence for intraaxonal spread of Listeria monocytogenes from the periphery to the central nervous system.单核细胞增生李斯特菌从外周向中枢神经系统轴突内扩散的证据。
Brain Pathol. 2001 Oct;11(4):432-8. doi: 10.1111/j.1750-3639.2001.tb00411.x.
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Aberrant macrophage and neutrophil population dynamics and impaired Th1 response to Listeria monocytogenes in colony-stimulating factor 1-deficient mice.集落刺激因子1缺陷小鼠中巨噬细胞和中性粒细胞群体动力学异常以及对单核细胞增生李斯特菌的Th1反应受损。
Infect Immun. 2001 Mar;69(3):1795-807. doi: 10.1128/IAI.69.3.1795-1807.2001.
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Listeria monocytogenes-infected phagocytes can initiate central nervous system infection in mice.感染单核细胞增生李斯特菌的吞噬细胞可引发小鼠中枢神经系统感染。
Infect Immun. 2001 Mar;69(3):1344-50. doi: 10.1128/IAI.69.3.1344-1350.2001.
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Neural route of cerebral Listeria monocytogenes murine infection: role of immune response mechanisms in controlling bacterial neuroinvasion.小鼠脑内单核细胞增生李斯特菌感染的神经途径：免疫反应机制在控制细菌神经侵袭中的作用。
Infect Immun. 2001 Feb;69(2):1093-100. doi: 10.1128/IAI.69.2.1093-1100.2001.
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Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo.体内吞噬性单核细胞向淋巴结树突状细胞的分化
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The M cell as a portal of entry to the lung for the bacterial pathogen Mycobacterium tuberculosis.M细胞作为细菌病原体结核分枝杆菌进入肺部的门户。
Immunity. 1999 Jun;10(6):641-50. doi: 10.1016/s1074-7613(00)80063-1.
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Dissemination of Listeria monocytogenes by infected phagocytes.被感染吞噬细胞对单核细胞增生李斯特菌的传播。
Infect Immun. 1999 Jul;67(7):3512-7. doi: 10.1128/IAI.67.7.3512-3517.1999.
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Phosphatidylcholine-specific phospholipase C from Listeria monocytogenes is an important virulence factor in murine cerebral listeriosis.来自单核细胞增生李斯特菌的磷脂酰胆碱特异性磷脂酶C是小鼠脑李斯特菌病中的一种重要毒力因子。
Infect Immun. 1998 Dec;66(12):5930-8. doi: 10.1128/IAI.66.12.5930-5938.1998.
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Interaction of Listeria monocytogenes with human brain microvascular endothelial cells: InlB-dependent invasion, long-term intracellular growth, and spread from macrophages to endothelial cells.单核细胞增生李斯特菌与人类脑微血管内皮细胞的相互作用：InlB 依赖性侵袭、长期细胞内生长以及从巨噬细胞向内皮细胞的扩散。
Infect Immun. 1998 Nov;66(11):5260-7. doi: 10.1128/IAI.66.11.5260-5267.1998.

集落刺激因子1依赖性细胞可抵御单核细胞增生李斯特菌的全身感染，但会促进神经侵袭。

Colony-stimulating factor 1-dependent cells protect against systemic infection with Listeria monocytogenes but facilitate neuroinvasion.

作者信息

Jin Yuxuan, Dons Lone, Kristensson Krister, Rottenberg Martin E

机构信息

Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

出版信息

Infect Immun. 2002 Aug;70(8):4682-6. doi: 10.1128/IAI.70.8.4682-4686.2002.

DOI:10.1128/IAI.70.8.4682-4686.2002
PMID:12117983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC128173/
Abstract

By using mice genomically lacking the mononuclear phagocytic growth factor colony-stimulating factor 1 and thereby deficient in macrophage and dendritic cell populations, we show that these cells play a dual role: they constitute a major defense against systemic infection but also facilitate cerebral bacterial invasion by Listeria monocytogenes.

摘要

通过使用基因上缺乏单核吞噬细胞生长因子集落刺激因子1从而巨噬细胞和树突状细胞群体存在缺陷的小鼠，我们发现这些细胞发挥着双重作用：它们构成了抵御全身感染的主要防线，但也促进了单核细胞增生李斯特菌对脑部的细菌侵袭。