[嗜酸性粒细胞样红斑：对抗疟药物有反应的韦尔斯嗜酸性粒细胞性蜂窝织炎的临床亚型？]
[Eosinophilic-like erythema: a clinical subset of Wells' eosinophilic cellulitis responding to antimalarial drugs?].
作者信息
Dereure O, Guilhou J J
机构信息
Service de Dermatologie-Phlébologie, Hôpital Saint-Eloi, 80, avenue Augustin Fliche, 34295 Montpellier Cedex 5, France.
出版信息
Ann Dermatol Venereol. 2002 May;129(5 Pt 1):720-3.
BACKGROUND
Limits of Wells'syndrome, a nosologically enlarged entity defined after classic eosinophilic cellulitis, are imprecise. We report on a new "frontier" case, remarkable in its clinical pattern and its high sensitivity to antimalarial drugs.
CASE REPORT
A 35-year-old woman was referred for evaluation of recurrent inflammatory, figurated and often annular lesions, mainly located on the trunk and the proximal parts of the limbs, associated with significant peripheral eosinophilia and featuring dense perivascular infiltrates throughout the dermis with abundant eosinophils but without any "flame figure". These lesions responded dramatically to protracted treatment with hydroxychloroquine.
DISCUSSION
The relationship of this affection to Wells' syndrome is discussed along with its possible similarities to the sparse reports of so-called eosinophilic annular erythema.
背景
韦尔斯综合征是在经典嗜酸性粒细胞性蜂窝织炎之后定义的一种分类学上扩大的疾病实体，其界限不明确。我们报告了一个新的“边缘”病例，其临床模式显著，对抗疟药物高度敏感。
病例报告
一名35岁女性因反复出现炎症性、形态多样且常为环形的皮损前来评估，皮损主要位于躯干和四肢近端，伴有显著的外周血嗜酸性粒细胞增多，真皮全层可见密集的血管周围浸润，有大量嗜酸性粒细胞，但无任何“火焰状图形”。这些皮损对羟氯喹的长期治疗反应显著。
讨论
探讨了这种疾病与韦尔斯综合征的关系，以及它与所谓嗜酸性环形红斑的稀疏报道可能存在的相似之处。
Zotero 插件